Determination of Losartan and Triamterene in Pharmaceutical Compounds and Urine Using Cathodic Adsorptive Stripping Voltammetry

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Determination of losartan and triamterene in pharmaceutical compounds and urine using cathodic adsorptive stripping voltammetry.

A square-wave voltammetric procedure for the electroanalytical determination of losartan and triamterene in Britton-Robinson buffer (pH 3.0, 0.1 mol L(-1)) as a supporting electrolyte containing 30 ng mL(-1) of copper ions was developed. Opposite to the case of triamterene, losartan can not be reduced at a mercury electrode alone, but a new peak appears at -0.25 V in the presence of copper due ...

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Simultaneous Determination of Captopril and Thioguanine in Pharmaceutical Compounds and Blood using Cathodic Adsorptive Stripping Voltammetry

Apresentamos um procedimento altamente seletivo e sensível para a determinação simultânea de captopril e de tioguanina baseado em processo de redissolução catódica adsortiva dos complexos de Cu(I)-captopril e de Cu(I)-tioguanina em um eletrodo gotejante de mercúrio. Captopril e tioguanina foram pré-concentrados na superfície da gota do eletrodo de mercúrio usando Cu(II) como sensor e tempo de a...

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Adsorptive Cathodic Stripping Voltammetric Determination of Ciprofloxacin in Bulk Powder, Pharmaceutical Dosage Forms and Urine

Purpose: To investigate the electro-reduction behaviour and determination of ciprofloxacin using a hanging mercury drop electrode. Methods: Cyclic voltammograms of ciprofloxacin recorded in Britton – Robinson buffers pH 2 – 5 exhibit a single irreversible cathodic peak. The dependence of the peak current and peak potential values on buffer (nature, pH and concentration) and accumulation conditi...

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Adsorptive Cathodic Stripping Voltammetric Determination of Cefoperazone in Bulk Powder, Pharmaceutical Dosage Forms, and Human Urine

The electroreduction behaviour and determination of cefoperazone using a hanging mercury drop electrode were investigated. Cyclic voltammograms of cefoperazone recorded in universal Britton-Robinson buffers pH 3-6 exhibited a single irreversible cathodic peak. The process was adsorption-controlled. Britton-Robinson buffer 0.04 M pH 4.0 was selected as a supporting electrolyte for quantitative p...

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Cathodic adsorptive stripping voltammetric determination of prednisolone in pharmaceutical preparation and human urine.

Differential pulse cathodic adsorptive stripping voltammetric method was developed for the determination of prednisolone based on electrochemical reduction of the drug at a hanging mercury drop electrode (HMDE) in 0.04 M Britton-Robinson buffer pH 3.5. The peak current varied linearly over the concentration range 7.21-144.2 ng/ml prednisolone with limit of detection and limit of quantification ...

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ژورنال

عنوان ژورنال: Analytical Sciences

سال: 2008

ISSN: 0910-6340,1348-2246

DOI: 10.2116/analsci.24.1449